Real-Time Fortitude Of Emtricitabine, Dolutegravir And Tenofovir In Pharmaceutical Dosage By Rp-Hplc Method Through Stability Studies
نویسندگان
چکیده
An accurate, an efficient, sensitive, stability indicting RP-HPLC method has designed and developed authenticated for the instantaneous determination of Emtricitabine, Dolutegravir Tenofovir by pharmaceutical dosage method. The retention time Emtricitabine (ECT) (DTG) (TEN) 2.088, 2.491 2.919 minutes respectively compared with standard drugs time.
منابع مشابه
Simultaneous estimation of tenofovir disoproxil, emtricitabine and efavirenz in tablet dosage form by RP-HPLC
A simple, precise, rapid and accurate reverse phase HPLC method in isocratic mode has been developed for the estimation of Tenofovir disoproxil, Emtricitabine and Efavirenz in tablet dosage form. A Hypersil BDS C18, 250x4.6 mm, 5 μm partical size, with mobile phase consisting of acetonitrile and 0.03 M KH2PO4 water (pH adjusted to 3.2 with orthophosphoric acid) in the ratio of 60:40 v/v was use...
متن کاملStability-Indicating RP-HPLC Method for the Determination of Ambrisentan and Tadalafil in Pharmaceutical Dosage Form
A simple, rapid, and highly selective RP-HPLC method was developed for the simultaneous determination of Ambrisentan (AMB) and Tadalafil (TADA) drug substances in the fixed dosage strength of 10 mg and 40 mg, respectively. Effective chromatographic separation was achieved using a Hypersil GOLD C18 column (150 mm × 4.6 mm internal diameter, 5 μm particle size) with a mobile phase composed of met...
متن کاملStability-Indicating RP-HPLC Method for Determination of Tamsulosin HCL in Pharmaceutical Dosage Form
A selective, specific and sensitive stability-indicating high-performance liquid chromatographic method was developed and validated for the determination of Tamsulosin in in pharmaceutical dosage forms. Celecoxib was used as Internal Standard (IS). The chromatographic conditions comprised of a reversed-phase Lichrocart / Lichrosphere C18 column (250 × 4.0 mm packed with 5) with mobile phase con...
متن کاملStability Indicating Rp-Hplc Method for the Estimation of Montelukast in Pharmaceutical Dosage Form
A simple, specific, accurate, precise and stability-indicating reverse phase high performance liquid chromatography (RP-HPLC) method is developed for estimation of montelukast in tablet dosage form. The HPLC method, C-8 Column consisting of (25mm x 4.6mm x 5um – BDS) i.d in isocratic mode, with mobile phase containing 0.01M Potassium di-hydrogen orthophosphate buffer and acetonitrile in the rat...
متن کاملMethod Development And Validation Of Ondansetron In Bulk And Pharmaceutical Dosage Form By Stability- Indicating RP-HPLC Method
A precise and feasible high-performance liquid chromatographic (HPLC) method for the analysis of antiemetic drug Ondansetron tablet dosage form has been developed. The analysis was carried out on a zodiac C18 (4.6 x 250mm, 5 mm) column, using a buffer (pH 2.2), acetonitrile (73:27) as the mobile phase using a low pressure gradient mode with flow rate at 1ml/min and analysis was performed at wav...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Pharmaceutical Negative Results
سال: 2022
ISSN: ['0976-9234', '2229-7723']
DOI: https://doi.org/10.47750/pnr.2022.13.s09.76